gerAB [2017-8-11 16:0:3]

nutrient receptor, germination response to L-alanine, triggers premature germination in response to morphological defects during sporulation

Locus: BSU33060

Isoelectric point: 9.60

Molecular weight: 41.30 kDa

Protein length: 365 aa

Gene length: 1095 bp

Function: germination response to L-alanine

Product: nutrient receptor

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Transporters → Transporters/ other → Amino acid transporters → APC superfamily
• Lifestyles → Sporulation → Germination → Germinant receptors
• Groups of genes → Membrane proteins

Gene

Coordinates: 3,392,199 → 3,393,296

Phenotypes of a mutant

• suppresses the defects of spoVV mutant spores PubMed

The protein

Catalyzed reaction/ biological activity

• triggers premature germination in response to morphological defects during sporulation PubMed

Paralogous protein(s)

• GerBB, GerKB, YndE

Localization

• predicted to be an integral membrane protein with ten membrane-spanning helices PubMed
• inner spore membrane PubMed

Expression and Regulation

Operons

• Genes: gerAA-gerAB-gerAC
  Description: PubMed

  Sigma factors

  • SigG: sigma factor, PubMed, in SigG regulon
  • SigF: sigma factor, PubMed, in SigF regulon

  Regulatory mechanism

  • SpoVT: repression, PubMed, in SpoVT regulon

  Regulation

  • expressed during sporulation in the forespore (SigF, SigG, SpoVT) PubMed

  Additional information

  • 1,100 molecules are present per spore PubMed

References

Reviews

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Original publications

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